Search results for " caso"
showing 10 items of 130 documents
La inserción de las ciudades en las redes globales a través de las relaciones financieras : El caso de la ciudad de Valencia
2014
La circulación de maestros franceses entre las diócesis de Zaragoza y Tortosa durante los siglos XVI y XVII. El caso de Pedro Pizarro
2018
Tomato sauce enriched with olive oil exerts greater effects on cardiovascular disease risk factors than raw tomato and tomato sauce: a randomized tri…
2016
Epidemiological studies have observed a negative association between tomato intake and the incidence of cardiovascular disease. As tomato sauces are usually cooked with the addition of oil, some studies have pointed out that both processes may increase the bioavailability of the bioactive compounds. However, the effect of consumption of raw tomatoes and tomato sauces on inflammation biomarkers and adhesion molecules related to atherosclerosis remains unknown. The aim of this study was to test the postprandial effects of a single dose of raw tomatoes (RT), tomato sauce (TS) and tomato sauce with refined olive oil (TSOO) on cardiovascular disease risk factors. We performed an open, prospectiv…
Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study.
2017
Background-The relationship between plasma concentrations of betaine and choline metabolism and major cardiovascular disease (CVD) end points remains unclear. We have evaluated the association between metabolites from the choline pathway and risk of incident CVD and the potential modifying effect of Mediterranean diet interventions. Methods and Results-We designed a case-cohort study nested within the PREDIMED (Prevention With Mediterranean Diet) trial, including 229 incident CVD cases and 751 randomly selected participants at baseline, followed up for 4.8 years. We used liquid chromatography-tandem mass spectrometry to measure, at baseline and at 1 year of follow-up, plasma concentrations …
Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients
2020
MET alterations may provide a potential biomarker to evaluate patients who will benefit from treatment with MET inhibitors. Therefore, the purpose of the present study is to investigate the utility of a liquid biopsy-based strategy to assess MET alterations in cancer patients. We analyzed MET amplification in circulating free DNA (cfDNA) from 174 patients with cancer and 49 healthy controls and demonstrated the accuracy of the analysis to detect its alteration in patients. Importantly, a significant correlation between cfDNA concentration and MET copy number (CN) in cancer patients (r = 0.57, p <
Plasma Metabolites Associated with Coffee Consumption: A Metabolomic Approach within the PREDIMED Study
2019
Few studies have examined the association of a wide range of metabolites with total and subtypes of coffee consumption. The aim of this study was to investigate associations of plasma metabolites with total, caffeinated, and decaffeinated coffee consumption. We also assessed the ability of metabolites to discriminate between coffee consumption categories. This is a cross-sectional analysis of 1664 participants from the PREDIMED study. Metabolites were semiquantitatively profiled using a multiplatform approach. Consumption of total coffee, caffeinated coffee and decaffeinated coffee was assessed by using a validated food frequency questionnaire. We assessed associations between 387 metabolit…
Clinical Features at Onset and Genetic Characterization of Pediatric and Adult Patients with TNF-α Receptor—Associated Periodic Syndrome (TRAPS): A S…
2020
This study explores demographic, clinical, and therapeutic features of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a cohort of 80 patients recruited from 19 Italian referral Centers. Patients’ data were collected retrospectively and then analyzed according to age groups (disease onset before or after 16 years) and genotype (high penetrance (HP) and low penetrance (LP) TNFRSF1A gene variants). Pediatric- and adult-onset were reported, respectively, in 44 and 36 patients; HP and LP variants were found, respectively, in 32 and 44 cases. A positive family history for recurrent fever was reported more frequently in the pediatric group than in the adult group (p<0.05…
Educatio siglo XXI : revista de la Facultad de Educación
2008
Este artículo se inscribe en el marco de una investigación más amplia y ya finalizada, en la que se han analizado las variantesorganizativas producidas en dos centros de Educación Primaria de la Comunidad Valenciana al introducir las tecnologías informáticas. En el análisis hemos optado por el enfoque cualitativo de investigación, y consideramos el estudio de casos como el recurso o instrumento metodológico más adecuado para tratar de estudiar dos organizaciones educativas, una de la red pública y otra de la concertada, con objeto de comprender las interacciones que en ellas se desarrollan y para percibir los cambios que experimentan las unidades organizativas intermedias al tratar de integ…
La reproducción asistida y la filiación. Especial referencia al caso de las parejas de mujeres homosexuales
2018
This paper analyses, in general, the evolution that has had the art. 7.3 LTRHA since its introduction by the Act 3/2007, 15 march. In that way, it shows which has been the legislator´s solution about the use of assisted reproduction tecniques by homosexual women couples. Likewise, it studies which resolutions on the matter have been more relevant in the last years. All this, to set out the legislator´s failure and the need to reformulate the filiation regime in face of the challenge that assisted reproduction implies.
¿El Estado de Derecho en peligro? El juez constitucional contra la Constitución y a favor de la reelección presidencial indefinida : caso Bolivia
2021
In Bolivia, the third term and the habilitation of former President Evo Morales to the 2019 presidential elections was allowed with the acquiescence of the Plurinational Constitutional Court. Despite the fact that the Constitution prohibited it and there was a referendum that rejected indefinite presidential re-election. This occurred through the judicialization of politics that produced a non-formal reform of the Constitution producing a case of abusive constitutionalism and the destabilization of the rule of law.